Covid-19 vaccine: four years later, the list of persistent symptoms is growing
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Acute Disseminated Encephalomyelitis (ADEM) and other rare neuro-inflammatory events
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What: Rare inflammation of brain and spinal cord; can cause neurologic deficits.
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Which vaccines: Reported as a signal in some large-scale safety surveillance datasets (rare).
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How common: Extremely rare — reported as safety signals requiring further study rather than confirmed causal relationships.
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Immune thrombocytopenia (ITP) / Low platelets (non-VITT)
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What: Low platelet counts leading to bleeding/bruising risk.
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Which vaccines: Reports have appeared across vaccine types; some cases were transient.
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How common: Rare; often manageable with standard therapies.
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